Naphthostyril
WitrynaIt was revealed that the most active compound N-(4-hydroxyphenyl)naphthostyril-1-sulfonamide inhibited FGFR1 with IC50 of 2 µM. In our preliminary studies, N-phenylnaphthostyril-1-sulfonamides demonstrated selectivity of FGFR1 inhibition … WitrynaProcess for the preparation of naphthostyril by dissolving 1,8-naphthalimide in an aqueous solution of lithium hydroxide and potassium hydroxide while heating at 40° …
Naphthostyril
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Witrynanaphthostyril type compounds suitable for dyeing or coloring hydrophobic man-made fibrous materials, particularly a polyester, polyester ether, acetyl cellulose or polyamide, are 1-w,2-(((x)m,(o2n-)phenyl)-n=),(y)n-1,2-dihydro benz(cd)indole where w is hydrogen, lower alkyl, phenyl (lower alkyl), or phenyl group; y is hydrogen, halogen, nitro, lower … Witryna1 paź 1982 · Naphthostyril (1) and isatin (2) were condensed with N-substituted homophthalimides (4) in the presence of phosphorus oxychloride to give violet to bl…
Witryna14 gru 2024 · Name:benz(cd)indol-2(1H)-one,CAS:130-00-7.Use:Intermediates for the synthesis of vat dyes and organic pigments.Buy Naphthostyril.Molecular … WitrynaNaphthostyril Ni or Cu complexes, a process for their preparation, and high molecular weight organic material pigmented with these metal complexes Jun 13, 1983 - Ciba-Geigy Corporation 1:2 Nickel or 1:2 copper complexes of a naphthostyril of the formula ##STR1## or of tautomers thereof, in which A, X and Y are as defined in claim 1, are ...
Witryna2 lut 2024 · Nootropil. Nootropil jest lekiem z grupy leków nootropowych. Zmniejsza lepkość krwi, zwiększa przepływ przez naczynia w mózgu, bez działania … Witryna1,8-萘内酰亚胺 - 基本信息. 173-178°C (lit.) 细针状结晶，熔点180-181℃。. 易溶于沸水，微溶于乙醚。. 22 - 吞食有害。. 24/25 - 避免与皮肤和眼睛接触。. 用1,8-萘二甲酰 …
Naphtholactam ist ein Derivat des bicyclischen aromatischen Kohlenwasserstoffs Naphthalin, das in 1,8-Position mit einer Lactamfunktion überbrückt ist. Die auch häufig als Naphthostyril bezeichnete Substanz ist ein Molekülbaustein für gelbe bis violette Dispersionsfarbstoffe und Pigmente der Naphtholactam-Reihe und wegen seiner anellierten Indolstruktur Ausgangsstoff für pharmakologisch aktive Verbindungen.
Witryna3-Pyrrolyl-6-fluoro-naphthostyril 13 was synthesized via a base-catalyzed intramolecular cyclization of oxindole precursor 2 (Y=H). Derivatization of 2 (Y=I) through a one-pot reaction give 5-substituted naphthostyrils. This method allows convenient access to 3,5,6-trisubstituted naphthostyrils which may serve as a new template for CDK2 … dsインサイト ログインWitryna4 sie 2003 · A novel class of 3,5,6-trisubstituted naphthostyril analogues was designed and synthesized to study the structure-activity relationship for inhibition of cyclin-dependent kinase 2 (CDK2). These compounds, particularly molecules with side-chain modifications providing additional hydrogen bonding capability, were demonstrated to … dsインサイト 料金WitrynaSearch for Chalcogen Bonded Directly To Ring Carbon Of The Five-membered Hetero Ring (e.g., Naphthostyril, Etc.) Patents and Patent Applications (Class 548/437) Filed with the USPTO ds いつまでWitrynanaphthostyril carboxylic acid dicarboxylic acid Prior art date 1940-01-26 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Lifetime Application number US315757A Inventor Frederic B Stilmar dsインサイト マニュアルWitryna18 sie 2024 · In this paper, a series of small molecules targeting Hsp90-Cdc37 complex are addressed and characterized. The molecules' key characters are determined by utilizing a structure-based virtual screening workflow, derivatives synthesis, and biological evaluation. Structural optimization and structure-activity relationship (SAR) analysis … dsインサイト ヤフーWitryna18 cze 2014 · Abstract New class of FGFR1 kinase inhibitors with naphthostyril heterocycle has been identified. A series of N-phenylnaphthostyril-1-sulfonamides has been synthesized and tested in vitro. dsインサイドWitrynaEXPERIMENTAL Reduction of Naphthostyril-10 gm. of sodium were added to a boiling solution of 2 gm. of naphthostyril in 200 cc. of dry butyl alcohol and the mixture was shaken vigorously. After the sodium had dissolved, water was added and the butyl alcohol was removed in a vacuum. dsインサイト 活用事例